Translational Implications of Platelets as Vascular First Responders

Resilience among first responders.

BACKGROUND Emergency rescue personnel can be considered a "high risk" occupational group in that they could experience a broad range of health and mental health consequences as a result of work-related exposures to critical incidents. OBJECTIVES This study examined the resilience factors that protect mental health among first responders. METHODS Nine hundred and sixty-one first responders f...

VoiceLETS backs up first responders

Food Safety for First Responders

508 Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 11, No. 3, March 2005 person-years) is substantially higher than the findings of Nennig and others (10) among an urban population in San Francisco (176 cases per 100,000 person-years). This finding may be due to the difference in immunization practices between Israel and the United States (5 doses of DTP vaccine in the United States with...

Platelets as cellular effectors of inflammation in vascular diseases.

Platelets are chief effector cells in hemostasis. In addition, they are multifaceted inflammatory cells with functions that span the continuum from innate immune responses to adaptive immunity. Activated platelets have key thromboinflammatory activities in a variety of vascular disorders and vasculopathies. Recently identified inflammatory and immune activities provide insights into the biology...

Platelets and Vascular

THE 12-LIPOXYGENASE ENZYME of platelets was the first lipoxygenase to be discovered in animal tissue,1 yet its physiologic significance remains far from clear. The enzyme catalyzes the reaction of arachidonic acid with molecular oxygen to form 12(S)-hydroperoxy-eicosatetraenoic acid (1 2-HPETE); under most conditions the majority of the hydroperoxide is reduced to the hydroxy form (1 2-HETE) an...